Caffeine may be the most popular legal addictive stimulant that is available to mankind. Besides coffee, tea, guarana and kola nut have excess amount of this xanthine alkaloid, which is actually acting as a psychoactive drug. In several plants, caffeine is an effective insect repellant, but this trimethylxanthine is deemed by the Food and Drug Administration as generally safe food substance. It is an antagonist of adenosine receptors. The effect of caffeine is individual and may more or less increase the ability to perform physical and mental labor. It reduces the effects of fatigue and may in long term help predominantly men reduce the risk of developing Parkinson’s disease. It has also been observed that caffeine has nootropic effects, furthermore, regular consumption of caffeine may significantly reduce the risk of heart diseases.

Chromium Polynicotinate, which is a form of chromium, an essential trace mineral that is needed for the body's production of insulin. Insulin is a hormone that stabilizes the body's blood sugar level.

Cocoa Seed Extract is the extract of the seeds of Theobroma cacao. It is cultivated for its seeds which are present in its pod shaped fruits. The extracts from its seeds have a number of health benefits. They are also used to make chocolate. Studies show that Cocoa extracts contain a high level of flavonoids, specifically epicatechin, which may have beneficial cardiovascular effects on health. The ingestion of flavonol-rich cocoa is associated with acute elevation of circulating nitric oxide, enhanced flow-mediated vasodilatation, and augmented microcirculation. Researchers also found that consumption of Cocoa can reduce risk of cancer and can reduce elevated blood pressure.

Evodiamine- Tetradii Fructus, the fruit of the evodia plant, also known as Tetradium rutaecarpa, contains an active element that has recently been identified as evodiamine. This chemical compound is believed to be somewhat similar to capsaicin, the active compound found in the chili peppers. Some studies suggested that this vanilloid receptor agonist may interact with thermogenin, otherwise known as the uncoupling protein 1, UCP1, which is able to generate heat by a mechanism called thermogenesis. Tetradium rutaecarpa has been traditionally used in Chinese medicine for weight loss purposes and current studies seem to verify this information. Evodiamine has been embraced as a dietary supplement directed at weight loss, predominantly by the body building circles. This supplement is deemed to have energy burning and fat reducing, as well as diuretic properties.

Garcinia Cambogia, which is used for the active ingredient, Hydrocitric Acid or HCA. It is extracted from the garcinia cambogia fruit, similar to an orange. It is commonly used as an appetite suppressant. Hydrocitric acid or HCA is a "lipogenesis inhibitor," which means that it slows down the production of fat from the metabolism of carbohydrates and proteins. This means that more calories are burned as energy and less are turned into stored fat. Studies on animals and humans have shown that HCA can suppress fat production and reduce appetite.

Ginger Root- Ginger is a spice which originated in Asia, where it is grown primarily in India and the Southeast of Asia. Currently it is used all over the world for culinary purposes. Several other uses, besides that of a spice, have been encountered, like in Ginger Ale, ginger tea, but also ginger beer. Gingerbread is perhaps the most popular example of ginger use, but historically it has been labeled as a stimulant and a carminative. Indonesia traditionally uses herbal preparations with ginger, which is supposed to reduce fatigue and help control all kind of digestive problems. Ginger is also known to help with morning sickness and is an ingredient in motion sickness remedies. Nausea in many forms, including chemotherapy, is treated with ginger as well.

Green Tea Extract increases energy expenditure and affects fat oxidation, which therefore promotes weight loss by increasing the body's metabolism.

Guarana is a climbing plant of the Sapindaceae family native to the Amazon basin. Guarana is best known for its fruit and seeds. Guarana extracts contain naturally high amounts of caffeine which the plant uses in defense against pathogens. Its extracts are a natural and abundant source of caffeine in most parts of the world. It is added to soft drinks, herbal tea, energy shots and used in capsules. The extracts have a positive effect on cognition and they also increase memory retention and physical endurance. A 2007 study on human pilots showed its positive effects on memory, alertness and mood. It is also reported to have antioxidant and antibacterial effects.

Hoodia Gordonii derives from a leafy plant and is utilized to suppress ones appetite.

Hordenine appears naturally in many grains, grassy plants, and in some species of hallucinogenic cactus and it is related to the amino acid tyramine. By stimulating norepinephrine release it helps in achieving weight loss by liberating lipids from adipose tissue. It has a big effect over the central nervous system with its attributes of stimulant. It has active ingredients slowing down food digestion. The effect of this is the ability to go longer without meals because it gives a satiating effect. Also known as N.N. dimethyltyramine, Hordenine is actually an indirectly acting adrenergic substance that’s easily available and also acts as an excitatory hormone that energizes the body as well. Those who want to suppress appetite and increase their energy also benefit from this supplement.

L-Tyrosine is a protein non-essential building block Although non-essential it is important for the structure of body proteins. It has a direct effect on neurotransmitters.

Octopamine is a secretion initially discovered in the salivary glands of the Octopus and hence the derivation of the name. it tendso to act as a neurotransmitter, transmitting messages from the neurons to the brain and vice versa. Octopamine has been found to have a tendency to release fat deposits from cells, thus aiding in the loss of weight. It is therefore being used as a slimming agent by most people, even though there is no concrete evidence that it does assist in weight loss, for sure. Octopamine is also believed to increase blood pressure levels when it is in combination with other weight loss stimulating supplements. Although not much is known about Octopamine, a deeper study is being conducted into its uses and effects.

Pantothenic Acid is also called vitamin B5 (a B vitamin). Its chemical formula is C9H17NO5 and Mol. Mass is 219.23 g mol-1 . It is a water soluble type of Vitamin B and an essential nutrient for life. Pantothenic acid is critical in the metabolism and synthesis of carbohydrates, proteins, and fats. It is used in some hair and skin care products .Pantothenic acid supplements are used to fulfill vitamin deficiency. Research also shows that these supplements reduce the duration of morning stiffness, degree of disability, and pain severity in rheumatoid arthritis patients.

Synephrine, More commonly called "bitter orange" or Citrus Aurantium, which is taken from unripe oranges. Research shows that citrus aurantium can increase the metabolic rate without affecting heart rate or blood pressure, breaks down fat, burns calories and may act as an appetite suppressant.

Vinpocetine is a derivitate of the periwinkle plant and was developed in the latter part of the 1960’s. It can be used as a dietary supplement, which can be found online.

White Willow Bark is used as an anti-inflammatory and treats pains such as joint pain, flu, fever, back pain and osteoarthritis.

Yerba Matte or Ilex paraguariensis commonly grows in South America. It contains about twenty four vitamins and minerals, fifteen amino acids, eleven types of polyphenols, caffeine, and contains a high level of antioxidants. It is considered to be the most balanced stimulant and revered as the “drink of the gods”. It contains xanthine alkaloids such as theobromine, caffeine and theophylline, and saponins that stimulate the immune system, enhance the memory and focus, and suppress appetite. Yerba Mate also helps regulate the blood sugar and cholesterol level. It also helps burn the fat and fight free radical damages to cells that may cause cancer and aging. It also helps in cleansing the blood, and may act as a diuretic