1-Androstene-3b-Ol,17-One is a compound rapidly becoming popular as a supplement for bodybuilders to increase testosterone levels. Before 1-Androstene-3b-Ol, 17-One came to shelves as a supplement 4-Androstenediol was the most popular supplement which gave great gains and libido increases, but it was banned worldwide by sports associations. 1-Androstene-3b-Ol, 17-One works similarly to 4-Androstenediol but it forms testosterone at a higher rate. The compound is converted to testosterone via the naturally occurring enzyme 3beta-HSD. It also does not convert to estrogen and/or DHT like older products. The use of 1-Androstene-3b-Ol, 17-One is legal and no association has yet objected to its use as a supplement.

Forskolin is an ingredient found in the Indian coleus plant, also known as Coleus forskohlii. It is a labdane diterpene that is currently very popular as a nutritional supplement, predominantly in the body building circles. The ability to raise the levels of cyclic adenosine monophosphate, cAMP, by deploying the enzyme adenylyl cyclase in the cAMP dependent pathway, made forskolin very important. Further benefits of forskolin include reduction of urinary tract infections, in connection with rolipram inhibition of colon cancer spreading, stimulation of proper tanning response with increased skin resistance to sun burns, reduction of intraocular pressure in glaucoma cases and apparently assistance in weight loss programs. Forskolin was observed to increase bone and lean mass as well as testosterone levels in clinical trials conducted with human test subjects.

Luteolin is a citrus flavonoid which may be found in parsley, thyme, peppermint, celery, artichoke and basil. It has anti-inflammatory effect that diminish the inflammation and pain which is beneficial to patients with arthritis. It is also an effect antioxidant that protects against free radicals from damaging the cells which may lead to serious diseases such as cancer. Luteolin promotes carbohydrate metabolism that helps in using carbohydrate as energy. It also helps control blood sugar level and aids in losing weight. Luteolin also alleviate the symptoms of septic shock. It also helps improve the immune system function and protects the body against infection.

Piperine is the substance responsible for the spiciness of pepper. It is of alkaloid in nature and is found in the plant species of the genus Piper of the Piperaceae family. The black pepper, Piper nigrum, has been utilized in the medicine system of Ayurveda for the treatment and management of different illnesses and diseases. Piperine has been found out to be more than just a spice component. In humans, piperine was observed to inactivate some enzymes that are crucial in metabolism of some drugs. The study of G. Shoba, T. Joseph, M. Majeed, R. Rajendran, and P.S. Srinivas of St. John’s Medical College in India about the influence of piperine on the pharmacokinetics of curcumin in animals and humans showed intriguing results. Curcumin is a substance found in the spice turmeric that has antioxidant and anti-inflammatory properties. Piperine increases the bioavailability of curcumin potentiating its effect in the body. Piperine has a biochemical name (IUPAC name) of 1-[5-(1,3-benzodioxol-5-yl)-1-oxo-2,4-pentadienyl]piperidine.

Sodium Caprylate, in sub-fungistatic concentrations, shows interesting effects on fatty acid synthesis, metabolism, and pigmentogenesis of Trichophyton rubrum during its earlier growth phases. It significantly reduces fatty acid concentration. Carboxylic acids (sodium caprylate) have been utilized in preparing plasma products (precipitation of globulins) and inactivation of lipid-coated virus, but when therapeutic biologically active proteins are not present. Sodium caprylate has also been applied in association with heat and amino acids for virus inactivation. It can provide a proper caprylic acid concentration for virus inactivation. Because of dissociation reaction, non-iodized caprylic acid can be kept at an increased concentration at higher pHs by raising concentration of the ionized form (sodium caprylate) to kill viruses.